Temporary use of remote nodes is useful in order to use Monero immediately (hence the name bootstrap), however be aware that when using remote nodes (including with the bootstrap setting), nodes could track your IP address, track your "restore height" and associated block request data, and send you inaccurate information to learn more about transactions you make.
This mode is ideal for managing small amounts of Monero. You have access to basic features for making and managing transactions. It will automatically connect to the Monero network so you can start using Monero immediately.
Remote nodes are useful if you are not able/don't want to download the whole blockchain, but be advised that malicious remote nodes could compromise some privacy. They could track your IP address, track your "restore height" and associated block request data, and send you inaccurate information to learn more about transactions you make.
Create portable wallets and use them on any PC. Enable if you installed Monero on a USB stick, an external drive, or any other portable storage medium.